“Clients are expected to
achieve 30% faster sensor-to-market
defined as the time required
from study requirements definition
to having the digital phenotyping
solution up and running.”
The case
Clinical trials are experiments on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments and known interventions for further study and comparison. The purpose is to generate data on safety and efficacy of a treatment or medication. Clinical trials follow after the pre-clinical or animal studies phase, with three phases of human trials involving hundreds to thousands of patients at multiple sites or countries.
A large life sciences company in Central Europe seeks a partner to help scout for sensors in specific therapeutic areas for its digital biomarkers, and to help improve the efficacy and efficiency of clinicals trials by employing advanced technology to collect patient data round-the-clock through enhanced patient monitoring, and to perform data analytics to interpret the data and generate insights at the shortest viable timeframe.
Why Atos?
Global life sciences organizations often face challenges with digital health solutions which require more devices and apps to be provisioned to support clinical trials’ data collection and insights generation. Atos helps in the digital transformation of clinical trials and improve process efficiency. It has good understanding of clinical research, patient, and care delivery pathways, and offers a solution focused on User Experience, with end-to-end global deployment services for the clinical trial kits. Atos adds measurable value to clinical trials by helping to scout and select sensors, as well as integrate and manage the clinical trial activities.
The large life sciences company has selected Atos to be its technology partner to help advance and accelerate the clinical research and development process with digital biomarkers.
The solution
Depending on the customer situation Atos can be involved at different stages to support the customer journey in sensor advisory and integration for clinical trials.
Phase 1: Market Research & Recommendation
During the initial phase, Atos performs market research to identify potential solutions that meet the specific requirements of the respective clinical trial. Potential sensors solutions are then further assessed against different criteria such as technical capabilities, deployability and usability. After a thoroughly conducted analysis Atos provides a detailed report with a ranking of sensors according to the defined scoring model and a final expert recommendation.
Phase 2: Sensor Testing & Data Analysis
At the next stage, a practical testing of one or multiple recommended devices can be conducted to test and eventually prove the sensor capabilities in real life scenarios. In support of the clinical trials, the testing for the digital biomarkers entail having human subjects of different ages to wear sensors which will collect specific test data in accordance with a defined protocol. For example, movement and posture which investigates physical movement patterns. The objective is to test the sensor from various perspectives, such as usability, data collection capabilities and the quality of data collected. The data generated is finally analyzed in order to prove the quality and reliability of the measurements performed during the testing phase.
As the key technology partner, Atos supports in designing the study with a range of potentially fitting sensors, and upon customer decision, proceed to set up, configure, and deploy the testing environment for the clinical trials, while ensuring end-to-end asset management. The real-world testing of the sensors is also the phase where massive amounts of data are collected. Following this, usability analysis and data analysis are performed with advanced analytics to draw insights where the recommendation of the most suitable sensor for the specific clinical trials is proposed.
As an additional benefit, the detailed and critical analysis of sensor and solution capabilities, robustness and reliability not only help the sponsor to determine the right solution for its clinical trial, but also the sensor provider to improve the capabilities and quality of the sensor offered to the market.
Outlook and potential next steps:
In the next step(s) the sensor could be further extended (e.g., by mobile apps, algorithms, etc.) and/or integrated into an existing platform to ensure a holistic solution for enhanced patient monitoring and insights generation. While the customer can have its own or preferred 3rd party platform for device integration, Atos offers different platform solutions through in-house and partner eco systems to fully support end-to-end sensor integration, data collection and insights generation to increase efficiency of clinical trials.
Moving forward, the integrated solution could be taken to the first feasibility study which can be a clinical trial.
Conclusion
The large life sciences company in Central Europe benefits from the digital capabilities and experience of Atos, which employs advanced technology in this solution. Working hand-in-hand with the life sciences company as one team, the development of digital biomarkers is accelerated. This ultimately helps improve the competitive position of the life sciences company while it focuses on improving patients’ lives.
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